Homology AFF664 vs Protein
Query= AFF664 (AFF664Q) /CSM/AF/AFF6-C/AFF664Q.Seq.d/
(753 letters)
Database: nrp_B
5,349,213 sequences; 1,732,582,204 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF275723_1(AF275723|pid:none) Dictyostelium discoideum Ras guani... 317 3e-85
(Q8IS15) RecName: Full=Ras guanine nucleotide exchange factor I;... 62 2e-08
(Q8IS14) RecName: Full=Ras guanine nucleotide exchange factor J;... 61 5e-08
(Q8SSW7) RecName: Full=Ras guanine nucleotide exchange factor S;... 59 2e-07
U53884_1(U53884|pid:none) Dictyostelium discoideum aimless RasGE... 58 4e-07
AY160090_1(AY160090|pid:none) Dictyostelium discoideum nucleotid... 58 4e-07
(Q54PQ4) RecName: Full=Ras guanine nucleotide exchange factor A;... 58 4e-07
AY160100_1(AY160100|pid:none) Dictyostelium discoideum nucleotid... 50 1e-04
AF474377_1(AF474377|pid:none) Dictyostelium discoideum Ras GTP e... 50 1e-04
(Q54FF3) RecName: Full=Ras guanine nucleotide exchange factor K;... 50 1e-04
AY160095_1(AY160095|pid:none) Dictyostelium discoideum nucleotid... 49 2e-04
(Q54C94) RecName: Full=Ras guanine nucleotide exchange factor F;... 49 3e-04
(Q8IS11) RecName: Full=Ras guanine nucleotide exchange factor O;... 45 0.004
FQ311472_15(FQ311472|pid:none) Sporisorium reilianum SRZ2 chromo... 43 0.019
AC115592_17(AC115592|pid:none) Dictyostelium discoideum chromoso... 42 0.032
(Q55GH9) RecName: Full=Ras guanine nucleotide exchange factor W;... 42 0.032
(P70392) RecName: Full=Ras-specific guanine nucleotide-releasing... 40 0.16
(A2CEA7) RecName: Full=Ras-specific guanine nucleotide-releasing... 40 0.16
HE601630_35(HE601630|pid:none) Schistosoma mansoni strain Puerto... 40 0.16
FN357308_23(FN357308|pid:none) Schistosoma mansoni genome sequen... 40 0.16
AK290135_1(AK290135|pid:none) Homo sapiens cDNA FLJ77032 partial... 39 0.21
AK301205_1(AK301205|pid:none) Homo sapiens cDNA FLJ50071 complet... 39 0.21
AK365743_1(AK365743|pid:none) Hordeum vulgare subsp. vulgare mRN... 39 0.36
(Q99JE4) RecName: Full=Ras-specific guanine nucleotide-releasing... 39 0.36
AB385192_1(AB385192|pid:none) Synthetic construct DNA, clone: pF... 39 0.36
CR858031_1(CR858031|pid:none) Pongo abelii mRNA; cDNA DKFZp459J1... 39 0.36
BC040275_1(BC040275|pid:none) Homo sapiens Ras protein-specific ... 39 0.36
AF023130_1(AF023130|pid:none) Homo sapiens Ras-GRF2 mRNA, partia... 39 0.36
CQ834804_1(CQ834804|pid:none) Sequence 675 from Patent WO2004058... 39 0.36
(O14827) RecName: Full=Ras-specific guanine nucleotide-releasing... 39 0.36
FQ857380_13(FQ857380|pid:none) Piriformospora indica PIRI_contig... 38 0.47
BT015294_1(BT015294|pid:none) Drosophila melanogaster GH01796 fu... 38 0.61
(P26675) RecName: Full=Protein son of sevenless; &A41216(A41216... 38 0.61
CU928174_466(CU928174|pid:none) Zygosaccharomyces rouxii strain ... 38 0.61
M83931_1(M83931|pid:none) Drosophila melanogaster son of sevenle... 38 0.61
BC143367_1(BC143367|pid:none) Homo sapiens son of sevenless homo... 37 0.80
S25714(S25714) son-of-sevenless-2 protein - mouse (fragment) &Z... 37 0.80
AK302825_1(AK302825|pid:none) Homo sapiens cDNA FLJ56976 complet... 37 0.80
CU928180_310(CU928180|pid:none) Kluyveromyces thermotolerans str... 37 0.80
AF251308_1(AF251308|pid:none) Caenorhabditis elegans guanine nuc... 37 0.80
A75965_1(A75965|pid:none) Sequence 1 from Patent WO9321314. 37 0.80
AY902349_1(AY902349|pid:none) Mus musculus strain CAST/EiJ son o... 37 0.80
AC006692_9(AC006692|pid:none) Caenorhabditis elegans cosmid T28F... 37 0.80
AB209277_1(AB209277|pid:none) Homo sapiens mRNA for son of seven... 37 0.80
(Q62245) RecName: Full=Son of sevenless homolog 1; Shor... 37 0.80
S25716(S25716;S21391) Ras guanine nucleotide exchange factor son... 37 0.80
AK140310_1(AK140310|pid:none) Mus musculus adult male adrenal gl... 37 0.80
(Q02384) RecName: Full=Son of sevenless homolog 2; Shor... 37 0.80
AM920436_178(AM920436|pid:none) Penicillium chrysogenum Wisconsi... 37 1.0
AX027844_1(AX027844|pid:none) Sequence 1 from Patent WO0040718. 37 1.0
AM920437_1749(AM920437|pid:none) Penicillium chrysogenum Wiscons... 37 1.0
FP929129_86(FP929129|pid:none) Leptosphaeria maculans JN3 lm_Sup... 37 1.4
BC091317_1(BC091317|pid:none) Rattus norvegicus RAS protein-spec... 37 1.4
AF441482_1(AF441482|pid:none) Homo sapiens alternate SOS1 (SOS1)... 37 1.4
AC019171_1(AC019171|pid:none) Homo sapiens BAC clone RP11-173C1 ... 37 1.4
(Q07889) RecName: Full=Son of sevenless homolog 1; Shor... 37 1.4
A37488(A37488)Ras guanine nucleotide exchange factor son-of-seve... 37 1.4
AB209140_1(AB209140|pid:none) Homo sapiens mRNA for son of seven... 37 1.4
CR382130_894(CR382130|pid:none) Yarrowia lipolytica strain CLIB1... 36 1.8
CP001081_192(CP001081|pid:none) Clostridium botulinum Ba4 str. 6... 36 1.8
HE576752_366(HE576752|pid:none) Naumovozyma castellii CBS 4309 c... 36 2.3
CP000963_275(CP000963|pid:none) Clostridium botulinum A3 str. Lo... 36 2.3
AP008230_3036(AP008230|pid:none) Desulfitobacterium hafniense Y5... 36 2.3
CU633900_651(CU633900|pid:none) Podospora anserina S mat+ genomi... 35 3.0
AE017356_184(AE017356|pid:none) Cryptococcus neoformans var. neo... 35 4.0
AP007162_207(AP007162|pid:none) Aspergillus oryzae RIB40 DNA, SC... 35 5.2
AM910983_23(AM910983|pid:none) Plasmodium knowlesi strain H chro... 34 8.8
AF032126_1(AF032126|pid:none) Drosophila melanogaster ral guanin... 34 8.8
(Q552M5) RecName: Full=Ras guanine nucleotide exchange factor Y;... 34 8.8
AC117082_5(AC117082|pid:none) Dictyostelium discoideum chromosom... 34 8.8
AE014296_2626(AE014296|pid:none) Drosophila melanogaster chromos... 34 8.8
CP001229_1180(CP001229|pid:none) Sulfurihydrogenibium azorense A... 34 8.8
AE014296_2623(AE014296|pid:none) Drosophila melanogaster chromos... 34 8.8
CP003012_388(CP003012|pid:none) Thielavia terrestris NRRL 8126 c... 34 8.8
AE014187_420(AE014187|pid:none) Plasmodium falciparum 3D7 chromo... 34 8.8
>AF275723_1(AF275723|pid:none) Dictyostelium discoideum Ras guanine
nucleotide exchange factor RasGEFB (gefB) mRNA, complete
cds.
Length = 1529
Score = 317 bits (813), Expect = 3e-85
Identities = 165/201 (82%), Positives = 165/201 (82%)
Frame = +3
Query: 3 REYXXXXXXXXXXXXXXVMINNRSIGKSFSTGNFSQPQPIMPSXXXXXXXXXXXXXXXXX 182
REY VMINNRSIGKSFSTGNFSQPQPIMPS
Sbjct: 948 REYNHSHHHLLSSSSNNVMINNRSIGKSFSTGNFSQPQPIMPSNGIGGSGGGGLGTTLSV 1007
Query: 183 XXXXIVGGLQSRSSSFEENQLQYAIESFMEVYNHLTSKDKVDTSIWLEEEKEDINVYYIN 362
IVGGLQSRSSSFEENQLQYAIESFMEVYNHLTSKDKVDTSIWLEEEKEDINVYYIN
Sbjct: 1008 GNGGIVGGLQSRSSSFEENQLQYAIESFMEVYNHLTSKDKVDTSIWLEEEKEDINVYYIN 1067
Query: 363 NTNIDDKFYRSIKYASLNQLILKLTCESNTELRFTKTFITTYRSFTTGDIFLMKLIQRYF 542
NTNID KFYRSIKYASLNQLILKLTCESNTELRFTKTFITTYRSFTTGDIFLMKLIQRYF
Sbjct: 1068 NTNIDGKFYRSIKYASLNQLILKLTCESNTELRFTKTFITTYRSFTTGDIFLMKLIQRYF 1127
Query: 543 TPNLKNIVPYQFVQKIQIPIQ 605
TPNLKNIVPYQFVQKIQIPIQ
Sbjct: 1128 TPNLKNIVPYQFVQKIQIPIQ 1148
Score = 73.6 bits (179), Expect = 1e-11
Identities = 35/53 (66%), Positives = 38/53 (71%)
Frame = +3
Query: 594 IPIQXXXXQGYPXEPXPSVLGXLCXLPHMSDKKKFEDDTYEXPILLEPQXVNK 752
+ IQ QGY +P PSVLG LC LPHMSDKKKFEDDTYE ILLEP+ K
Sbjct: 1469 LEIQQYQQQGYTIKPKPSVLGFLCELPHMSDKKKFEDDTYEQSILLEPKNSTK 1521
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 5349213
Number of Hits to DB: 1,336,694,111
Number of extensions: 20037266
Number of successful extensions: 53851
Number of sequences better than 10.0: 75
Number of HSP's gapped: 53507
Number of HSP's successfully gapped: 76
Length of query: 251
Length of database: 1,732,582,204
Length adjustment: 129
Effective length of query: 122
Effective length of database: 1,042,533,727
Effective search space: 127189114694
Effective search space used: 127189114694
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 31 (16.5 bits)
Dictyostelium discoideum cDNA Project Home